Mitochondrially targeted ceramide preferentially promotes autophagy, retards cell growth, and induces apoptosis
نویسندگان
چکیده
1 Department of Pharmacology, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100050, P R China 2 Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina 29425 Research Center of Life Science, University of South China, Hengyang, Hunan 421001, P R China 4 Department of Medicine, Medical University of South Carolina, Charleston, South Carolina 29425 5 Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina 29401
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Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy
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